July 7, 2025

A Daily Pill for Dog Lymphoma? The Promise of Monepantel Explained | Kim Agnew, BVSc #287

A sheep dewormer shows promise in fighting dog lymphoma. Learn how Monepantel may offer hope for future dogs with cancer in this fascinating episode.

Originally aired in 2023, Molly Jacobson interviews Dr. Kim Agnew about the groundbreaking trials of Monepantel, a sheep dewormer repurposed as a potential treatment for canine lymphoma. Discover the science behind this innovative therapy, its potential to stabilize lymphoma, and how it compares to traditional treatments like chemotherapy and prednisone. 

 

Key Topics: 

  • What is Monepantel, and how was it discovered? 
  • The mechanism behind Monepantel's ability to target cancer cells. 
  • Early trial results: Quality of life and stability for dogs with B-cell lymphoma. 
  • How Monepantel compares to prednisone and chemotherapy. 
  • Insights into ongoing and future clinical trials. 
  • How dog lovers can participate in studies. 

 

Your Voice Matters!  

If you have a question for our team, or if you want to share your own hopeful dog cancer story, we want to hear from you! Go to https://www.dogcancer.com/ask to submit your question or story, or call our Listener Line at +1 808-868-3200 to leave a question.  

 

Related Videos: 

https://www.youtube.com/watch?v=_92w6TTXM5c  

https://www.youtube.com/watch?v=uAZrPM1X8ww  

 

Related Links: 

PharmAust Dog Lymphoma Clinical Trial: https://www.pharmaust.com/petdogtrial/ 

 

Chapters: 

00:00 Introduction 

00:30 Meet Dr. Kim Agnew and Monepantel Overview 

01:15 The Origin of Monepantel: From Dewormer to Cancer Fighter 

03:30 How Monepantel Targets Cancer Cells 

07:00 Insights on Clinical Trials for Canine Lymphoma 

09:30 Benefits of Monepantel: A Daily Pill for Dogs 

12:00 Comparing Monepantel to Chemotherapy and Prednisone 

14:45 Early Trial Results: Stabilizing Lymphoma in Dogs 

18:30 Why Lymphoma Was Chosen for Trials 

20:00 Potential for Treating Other Cancers in Dogs 

23:15 How to Enroll Dogs in Clinical Trials 

26:45 Side Effects and Safety of Monepantel 

31:00 Future Trials and Research Goals 

34:30 Closing Thoughts and Resources 

33:55 Closing Remarks and Resources 

 

Get to know Kim Agnew, BVSc:

https://www.dogcancer.com/people/kim-agnew-bvsc/    

For more details, articles, podcast episodes, and quality education, go to the episode page: https://www.dogcancer.com/podcast/  

 

Learn more about your ad choices. Visit megaphone.fm/adchoices