Insider Look at Rabacfosadine (Tanovea) from Shelved Human Drug to Dog Lymphoma Treatment | Dr. Doug Thamm #284

Dr. Doug Thamm discusses the development and use of Tanovea, a drug for treating lymphoma in dogs. He explains the drug's origins, initially researched as a human cancer therapeutic in collaboration with Gilead Sciences, and its transition to veterinary use.

Dr. Thamm provides insights into Tanovea’s application, dosage, and effectiveness compared to the CHOP protocol, as well as its potential side effects and other possible uses in different cancer types like multiple myeloma. The episode also delves into related immunotherapy research and personal reflections from Dr. Thamm, a double cancer survivor, on his career choice in veterinary oncology.

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Related Videos:

https://www.youtube.com/watch?v=G0iRyKshzq8

Related Links:

Our article on lymphoma: https://www.dogcancer.com/articles/types-of-dog-cancer/lymphoma-in-dogs/

Our article on Tanovea: https://www.dogcancer.com/articles/drugs/tanovea-rabacfosadine-chemotherapy/

Get the facts on dog cancer remission: https://www.dogcancer.com/articles/stats-and-facts/dog-cancer-remission/

Chapters:

00:00 Introduction

00:13 Interview with Dr. Doug Thamm

00:26 The Early Involvement with Tanovea

00:41 Challenges and Discoveries in Drug Development

02:16 Transition from Human to Veterinary Use

02:48 Clinical Trials and Dosage Experiments

06:45 FDA Approval and Practical Use

08:05 Comparing Tanovea and CHOP Protocol

15:23 Exploring Alternative Treatments: Laverdia

18:43 Off-Label Uses and Future Research

23:46 Exploring Tanovea's Effectiveness in Blood Cancers

25:14 Cost Comparison: Tanovea vs. CHOP

26:15 Side Effects of Tanovea

28:47 Pulmonary Fibrosis and Breed-Specific Risks

32:52 Personal Cancer Journeys: Dr. Doug and His Wife

38:23 Debunking Myths About Dog Cancer Treatment

42:24 The Future of Cancer Treatment: Immunotherapy

45:23 Conclusion and Resources

Get to know Dr. Doug Thamm:

https://www.dogcancer.com/people/doug-Thammm-v-m-d-diplomate-acvim-oncology/

For more details, articles, podcast episodes, and quality education, go to the episode page: https://www.dogcancer.com/podcast/

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