April 11, 2022

Tanovea: The First FDA-Approved Dog Lymphoma Treatment | Dr. Douglas Thamm #162

Born in a human drug research company, Tanovea (rabacfosadine) is now making history treating lymphoma in dogs.

Lymphoma in dogs is very responsive to chemotherapy, but it also often relapses. Each time a dog comes out of remission, the cancer often gets harder to beat. Because of this, researchers are constantly looking for new treatments that can either get long-lasting results from the start or be used to beat back the cancer in those difficult cases.

Meet rabacfosadine, known by the brand name Tanovea. This drug is an injectable chemotherapeutic that just became the first ever FDA-approved treatment for lymphoma in dogs. Dr. Douglas Thamm, an oncologist at Colorado State University, has been working with Tanovea through most of its existence, and tells us all about how this drug came to be, how it works, and what we know so far about when it is most useful.

Links Mentioned in Today’s Show:

T-CHOP NAÏVE CANINE LYMPHOMA STUDY at Colorado State

Clinical Trials at University of Wisconsin

Clinical Trials at Oregon State University

About Today’s Guest, Dr. Doug Thamm:

Dr. Thamm is the Barbara Cox Anthony Professor of Oncology and Director of Clinical Research at the Colorado State University Flint Animal Cancer Center. He is also a member of the Developmental Therapeutics Section of the University of Colorado Comprehensive Cancer Center and the Cell and Molecular Biology Graduate Program at Colorado State University. He has authored over 170 peer-reviewed publications and 20 book chapters in veterinary and basic cancer research, is Co-Editor for the most recent edition of the textbook Withrow and MacEwen’s Small Animal Clinical Oncology, and is Co-Editor-In-Chief of the journal Veterinary and Comparative Oncology. His clinical and research interests include novel targeted therapies for animal and human cancer and ways to integrate these therapies with existing treatment.

Other Links:

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